I19F (p.Ile19Phe) variant of IL18 (Interleukin-18)
I19F (p.Ile19Phe) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
I19F (p.Ile19Phe) variant details
- p.Ile19Phe
- ExAC rs766654584
- gnomAD rs766654584
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.32
- MetaLR 0.15
- MetaSVM -0.70
- CADD 23.20
- PolyPhen-2 0.55
- SIFT 0.04
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available