I11V (p.Ile11Val) variant of IL18 (Interleukin-18)
I11V (p.Ile11Val) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
I11V (p.Ile11Val) variant details
- p.Ile11Val
- gnomAD rs1261098651
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.01
- MetaLR 0.08
- MetaSVM -1.05
- CADD 9.25
- PolyPhen-2 0.01
- SIFT 0.06
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available