E7D (p.Glu7Asp) variant of IL18 (Interleukin-18)
E7D (p.Glu7Asp) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
E7D (p.Glu7Asp) variant details
- p.Glu7Asp
- Ensembl rs1866509618
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.05
- MetaLR 0.12
- MetaSVM -0.94
- CADD 5.45
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available