E34G (p.Glu34Gly) variant of IL18 (Interleukin-18)
E34G (p.Glu34Gly) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
E34G (p.Glu34Gly) variant details
- p.Glu34Gly
- gnomAD 11-112150197-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.44
- MetaLR 0.41
- MetaSVM -0.10
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available
- Literature evidence available