E34D (p.Glu34Asp) variant of IL18 (Interleukin-18)
E34D (p.Glu34Asp) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
E34D (p.Glu34Asp) variant details
- p.Glu34Asp
- gnomAD 11-112150196-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- REVEL 0.65
- MetaLR 0.29
- MetaSVM -0.45
- CADD 23.70
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available