D76E (p.Asp76Glu) variant of IL18 (Interleukin-18)
D76E (p.Asp76Glu) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
D76E (p.Asp76Glu) variant details
- p.Asp76Glu
- gnomAD rs1285841242
- Missense
- Variant Prioritization Score for Impact Estimate 0.0751
- REVEL 0.03
- MetaLR 0.02
- MetaSVM -0.93
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 4e-06)
- Structural context available