D76A (p.Asp76Ala) variant of IL18 (Interleukin-18)
D76A (p.Asp76Ala) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
D76A (p.Asp76Ala) variant details
- p.Asp76Ala
- TOPMed rs1866383862
- Missense
- Variant Prioritization Score for Impact Estimate 0.0765
- REVEL 0.02
- MetaLR 0.02
- MetaSVM -0.96
- CADD 3.46
- PolyPhen-2 0.00
- SIFT 0.58
- Most common in the East Asian population (allele frequency 3.1e-05)
- Structural context available