D59Y (p.Asp59Tyr) variant of IL18 (Interleukin-18)
D59Y (p.Asp59Tyr) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
D59Y (p.Asp59Tyr) variant details
- p.Asp59Tyr
- gnomAD 11-112150123-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.01
- MetaLR 0.08
- MetaSVM -0.98
- CADD 15.60
- PolyPhen-2 0.04
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available