D59E (p.Asp59Glu) variant of IL18 (Interleukin-18)
D59E (p.Asp59Glu) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
D59E (p.Asp59Glu) variant details
- p.Asp59Glu
- gnomAD 11-112150121-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.02
- MetaLR 0.11
- MetaSVM -0.99
- CADD 6.46
- PolyPhen-2 0.01
- SIFT 0.45
- Population evidence available
- Structural context available
- Literature evidence available