D53Y (p.Asp53Tyr) variant of IL18 (Interleukin-18)
D53Y (p.Asp53Tyr) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
D53Y (p.Asp53Tyr) variant details
- p.Asp53Tyr
- gnomAD 11-112150141-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.16
- MetaLR 0.21
- MetaSVM -0.70
- CADD 19.60
- PolyPhen-2 0.67
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available