D30G (p.Asp30Gly) variant of IL18 (Interleukin-18)
D30G (p.Asp30Gly) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
D30G (p.Asp30Gly) variant details
- p.Asp30Gly
- TOPMed rs972965703
- gnomAD rs972965703
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.24
- MetaLR 0.13
- MetaSVM -0.94
- CADD 26.00
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available