A78V (p.Ala78Val) variant of IL18 (Interleukin-18)
A78V (p.Ala78Val) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A78V (p.Ala78Val) variant details
- p.Ala78Val
- gnomAD rs1242480821
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.07
- MetaLR 0.08
- MetaSVM -1.07
- CADD 17.40
- PolyPhen-2 0.77
- SIFT 0.06
- Most common in the South Asian population (allele frequency 1.6e-05)
- Structural context available