A78S (p.Ala78Ser) variant of IL18 (Interleukin-18)
A78S (p.Ala78Ser) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
A78S (p.Ala78Ser) variant details
- p.Ala78Ser
- gnomAD 11-112148731-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.136
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -1.01
- CADD 13.70
- PolyPhen-2 0.47
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available