S6G (p.Ser6Gly) variant of IL17RA (Interleukin-17 receptor A)
S6G (p.Ser6Gly) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
S6G (p.Ser6Gly) variant details
- p.Ser6Gly
- gnomAD 22-17085107-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0929
- REVEL 0.07
- MetaLR 0.01
- MetaSVM -0.91
- CADD 0.87
- PolyPhen-2 0.01
- SIFT 0.95
- Most common in the Non-Finnish European population (allele frequency 2e-06)
- Structural context available
- Literature evidence available