S32C (p.Ser32Cys) variant of IL17RA (Interleukin-17 receptor A)
S32C (p.Ser32Cys) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S32C (p.Ser32Cys) variant details
- p.Ser32Cys
- TOPMed rs1167001946
- gnomAD rs1167001946
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.06
- MetaLR 0.07
- MetaSVM -1.05
- CADD 23.60
- PolyPhen-2 0.52
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available