L26V (p.Leu26Val) variant of IL17RA (Interleukin-17 receptor A)
L26V (p.Leu26Val) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L26V (p.Leu26Val) variant details
- p.Leu26Val
- TOPMed rs1335482114
- gnomAD rs1335482114
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.04
- MetaLR 0.02
- MetaSVM -1.01
- CADD 11.00
- PolyPhen-2 0.14
- SIFT 0.51
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available