L22R (p.Leu22Arg) variant of IL17RA (Interleukin-17 receptor A)
L22R (p.Leu22Arg) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
L22R (p.Leu22Arg) variant details
- p.Leu22Arg
- gnomAD 22-17085156-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.12
- CADD 14.60
- PolyPhen-2 0.38
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available