L21V (p.Leu21Val) variant of IL17RA (Interleukin-17 receptor A)
L21V (p.Leu21Val) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L21V (p.Leu21Val) variant details
- p.Leu21Val
- TOPMed rs2061321574
- Missense
- Variant Prioritization Score for Impact Estimate 0.136
- REVEL 0.04
- MetaLR 0.03
- MetaSVM -1.04
- CADD 7.90
- PolyPhen-2 0.43
- SIFT 0.98
- Most common in the Latino/Admixed American population (allele frequency 3e-05)
- Structural context available