L21R (p.Leu21Arg) variant of IL17RA (Interleukin-17 receptor A)
L21R (p.Leu21Arg) in IL17RA (Interleukin-17 receptor A) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L21R (p.Leu21Arg) variant details
- p.Leu21Arg
- rs1172016907
- gnomAD 22-17085152-CT-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.344
- CADD 22.60
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available