L16V (p.Leu16Val) variant of IL17RA (Interleukin-17 receptor A)
L16V (p.Leu16Val) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
L16V (p.Leu16Val) variant details
- p.Leu16Val
- gnomAD rs1425048324
- Missense
- Variant Prioritization Score for Impact Estimate 0.153
- REVEL 0.03
- MetaLR 0.03
- MetaSVM -1.03
- CADD 10.70
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the Latino/Admixed American population (allele frequency 3.2e-05)
- Structural context available