L16R (p.Leu16Arg) variant of IL17RA (Interleukin-17 receptor A)
L16R (p.Leu16Arg) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
L16R (p.Leu16Arg) variant details
- p.Leu16Arg
- ExAC rs752093297
- gnomAD rs752093297
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.09
- MetaLR 0.03
- MetaSVM -1.04
- CADD 21.80
- PolyPhen-2 0.50
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available