G30S (p.Gly30Ser) variant of IL17RA (Interleukin-17 receptor A)
G30S (p.Gly30Ser) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G30S (p.Gly30Ser) variant details
- p.Gly30Ser
- TOPMed rs1215508376
- gnomAD rs1215508376
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.01
- MetaLR 0.02
- MetaSVM -1.00
- CADD 10.30
- PolyPhen-2 0.00
- SIFT 0.76
- Most common in the African/African-American population (allele frequency 6.7e-05)
- Structural context available