G2E (p.Gly2Glu) variant of IL17RA (Interleukin-17 receptor A)
G2E (p.Gly2Glu) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
G2E (p.Gly2Glu) variant details
- p.Gly2Glu
- gnomAD 22-17085096-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.08
- MetaLR 0.01
- MetaSVM -0.96
- CADD 21.60
- PolyPhen-2 0.42
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 3e-06)
- Structural context available
- Literature evidence available