G24S (p.Gly24Ser) variant of IL17RA (Interleukin-17 receptor A)
G24S (p.Gly24Ser) in IL17RA (Interleukin-17 receptor A) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
G24S (p.Gly24Ser) variant details
- p.Gly24Ser
- 1000Genomes rs41510847
- ExAC rs41510847
- TOPMed rs41510847
- gnomAD rs41510847
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.0809
- REVEL 0.02
- MetaLR 0.01
- MetaSVM -0.94
- CADD 5.58
- PolyPhen-2 0.00
- SIFT 1.00
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available