G17A (p.Gly17Ala) variant of IL17RA (Interleukin-17 receptor A)
G17A (p.Gly17Ala) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G17A (p.Gly17Ala) variant details
- p.Gly17Ala
- TOPMed rs1568914031
- gnomAD rs1568914031
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.03
- MetaLR 0.02
- MetaSVM -0.96
- CADD 8.59
- PolyPhen-2 0.07
- SIFT 0.57
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available