A4T (p.Ala4Thr) variant of IL17RA (Interleukin-17 receptor A)
A4T (p.Ala4Thr) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
A4T (p.Ala4Thr) variant details
- p.Ala4Thr
- TOPMed rs1464593132
- gnomAD rs1464593132
- Missense
- Variant Prioritization Score for Impact Estimate 0.136
- REVEL 0.03
- MetaLR 0.01
- MetaSVM -0.94
- CADD 8.38
- PolyPhen-2 0.02
- SIFT 0.28
- Most common in the South Asian population (allele frequency 1.9e-05)
- Structural context available