A4P (p.Ala4Pro) variant of IL17RA (Interleukin-17 receptor A)
A4P (p.Ala4Pro) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
A4P (p.Ala4Pro) variant details
- p.Ala4Pro
- gnomAD 22-17085101-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.08
- MetaLR 0.01
- MetaSVM -0.91
- CADD 7.83
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 7.3e-05)
- Structural context available
- Literature evidence available