A10T (p.Ala10Thr) variant of IL17RA (Interleukin-17 receptor A)
A10T (p.Ala10Thr) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
A10T (p.Ala10Thr) variant details
- p.Ala10Thr
- 1000Genomes rs758765484
- ExAC rs758765484
- TOPMed rs758765484
- gnomAD rs758765484
- Missense
- Variant Prioritization Score for Impact Estimate 0.0924
- REVEL 0.02
- MetaLR 0.01
- MetaSVM -0.94
- CADD 11.30
- PolyPhen-2 0.03
- SIFT 0.27
- Most common in the 1KG:FIN population (allele frequency 0.0051)
- Structural context available