A10D (p.Ala10Asp) variant of IL17RA (Interleukin-17 receptor A)
A10D (p.Ala10Asp) in IL17RA (Interleukin-17 receptor A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
A10D (p.Ala10Asp) variant details
- p.Ala10Asp
- gnomAD 22-17085120-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.09
- MetaLR 0.01
- MetaSVM -0.93
- CADD 8.46
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Ashkenazi Jewish population (allele frequency 5.1e-05)
- Structural context available
- Literature evidence available