Y60C (p.Tyr60Cys) variant of IL12RB1 (P42701)
Y60C (p.Tyr60Cys) in IL12RB1 (P42701) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data.
Y60C (p.Tyr60Cys) variant details
- p.Tyr60Cys
- ESP rs140770932
- ExAC rs140770932
- TOPMed rs140770932
- gnomAD rs140770932
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- CADD 23.30
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00031)