V5L (p.Val5Leu) variant of IL12RB1 (P42701)
V5L (p.Val5Leu) in IL12RB1 (P42701) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
V5L (p.Val5Leu) variant details
- p.Val5Leu
- gnomAD rs1568526239
- Missense
- Variant Prioritization Score for Impact Estimate 0.61
- CADD 16.10
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available