C86Y (p.Cys86Tyr) variant of IL12RB1 (P42701)
C86Y (p.Cys86Tyr) in IL12RB1 (P42701) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data.
C86Y (p.Cys86Tyr) variant details
- p.Cys86Tyr
- ExAC rs753438288
- gnomAD rs753438288
- Missense
- Variant Prioritization Score for Impact Estimate 0.651
- CADD 24.00
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00015)