W60* (p.Trp60Ter) variant of IL12B (Interleukin-12 subunit beta)
W60* (p.Trp60Ter) in IL12B (Interleukin-12 subunit beta) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
W60* (p.Trp60Ter) variant details
- p.Trp60Ter
- TOPMed rs1324674540
- gnomAD rs1324674540
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.854
- CADD 36.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available