W37R (p.Trp37Arg) variant of IL12B (Interleukin-12 subunit beta)
W37R (p.Trp37Arg) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
W37R (p.Trp37Arg) variant details
- p.Trp37Arg
- gnomAD rs1177833515
- Missense
- Variant Prioritization Score for Impact Estimate 0.455
- REVEL 0.40
- MetaLR 0.14
- MetaSVM -0.94
- CADD 25.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available