V68F (p.Val68Phe) variant of IL12B (Interleukin-12 subunit beta)
V68F (p.Val68Phe) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
V68F (p.Val68Phe) variant details
- p.Val68Phe
- TOPMed rs1015688626
- gnomAD rs1015688626
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.02
- CADD 10.10
- PolyPhen-2 0.29
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 1.1e-05)
- Structural context available