V14F (p.Val14Phe) variant of IL12B (Interleukin-12 subunit beta)
V14F (p.Val14Phe) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
V14F (p.Val14Phe) variant details
- p.Val14Phe
- ExAC rs779736965
- TOPMed rs779736965
- gnomAD rs779736965
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.14
- MetaLR 0.05
- MetaSVM -1.06
- CADD 18.20
- PolyPhen-2 0.07
- SIFT 0.60
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available