S98R (p.Ser98Arg) variant of IL12B (Interleukin-12 subunit beta)
S98R (p.Ser98Arg) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
S98R (p.Ser98Arg) variant details
- p.Ser98Arg
- gnomAD rs1431364350
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.25
- MetaLR 0.15
- MetaSVM -0.87
- CADD 22.80
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available