Q78P (p.Gln78Pro) variant of IL12B (Interleukin-12 subunit beta)
Q78P (p.Gln78Pro) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
Q78P (p.Gln78Pro) variant details
- p.Gln78Pro
- TOPMed rs1361534479
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.16
- MetaLR 0.06
- MetaSVM -1.02
- CADD 17.30
- PolyPhen-2 0.23
- SIFT 0.06
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available