Q64R (p.Gln64Arg) variant of IL12B (Interleukin-12 subunit beta)
Q64R (p.Gln64Arg) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
Q64R (p.Gln64Arg) variant details
- p.Gln64Arg
- ESP rs150659914
- TOPMed rs150659914
- gnomAD rs150659914
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.05
- MetaLR 0.04
- MetaSVM -0.97
- CADD 0.82
- PolyPhen-2 0.00
- SIFT 0.24
- Most common in the African/African-American population (allele frequency 9.6e-05)
- Structural context available