P123T (p.Pro123Thr) variant of IL12B (Interleukin-12 subunit beta)
P123T (p.Pro123Thr) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
P123T (p.Pro123Thr) variant details
- p.Pro123Thr
- gnomAD 5-159322509-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.04
- MetaLR 0.06
- MetaSVM -1.06
- CADD 21.50
- PolyPhen-2 0.32
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available