N135D (p.Asn135Asp) variant of IL12B (Interleukin-12 subunit beta)
N135D (p.Asn135Asp) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
N135D (p.Asn135Asp) variant details
- p.Asn135Asp
- gnomAD 5-159322473-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.11
- MetaLR 0.07
- MetaSVM -1.08
- CADD 23.20
- PolyPhen-2 0.28
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available