K126R (p.Lys126Arg) variant of IL12B (Interleukin-12 subunit beta)
K126R (p.Lys126Arg) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
K126R (p.Lys126Arg) variant details
- p.Lys126Arg
- gnomAD 5-159322499-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.10
- MetaLR 0.06
- MetaSVM -1.10
- CADD 19.00
- PolyPhen-2 0.01
- SIFT 0.37
- Population evidence available
- Structural context available
- Literature evidence available