I77V (p.Ile77Val) variant of IL12B (Interleukin-12 subunit beta)
I77V (p.Ile77Val) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
I77V (p.Ile77Val) variant details
- p.Ile77Val
- ExAC rs778518679
- gnomAD rs778518679
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.03
- MetaLR 0.04
- MetaSVM -0.96
- CADD 15.10
- PolyPhen-2 0.00
- SIFT 0.79
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available