G57V (p.Gly57Val) variant of IL12B (Interleukin-12 subunit beta)
G57V (p.Gly57Val) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G57V (p.Gly57Val) variant details
- p.Gly57Val
- gnomAD rs1382273910
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.07
- MetaLR 0.03
- MetaSVM -1.01
- CADD 17.90
- PolyPhen-2 0.16
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available