G57D (p.Gly57Asp) variant of IL12B (Interleukin-12 subunit beta)
G57D (p.Gly57Asp) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
G57D (p.Gly57Asp) variant details
- p.Gly57Asp
- gnomAD rs1382273910
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.07
- MetaLR 0.02
- MetaSVM -0.97
- CADD 12.90
- PolyPhen-2 0.00
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available