F128C (p.Phe128Cys) variant of IL12B (Interleukin-12 subunit beta)
F128C (p.Phe128Cys) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
F128C (p.Phe128Cys) variant details
- p.Phe128Cys
- 1000Genomes rs183576218
- ExAC rs183576218
- gnomAD rs183576218
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.28
- MetaLR 0.12
- MetaSVM -0.99
- CADD 26.60
- SIFT 0.00
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available