E81G (p.Glu81Gly) variant of IL12B (Interleukin-12 subunit beta)
E81G (p.Glu81Gly) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
E81G (p.Glu81Gly) variant details
- p.Glu81Gly
- 1000Genomes rs540842370
- ExAC rs540842370
- gnomAD rs540842370
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.29
- MetaLR 0.15
- MetaSVM -0.93
- CADD 27.10
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the 1KG:GIH population (allele frequency 0.02)
- Structural context available