E132* (p.Glu132Ter) variant of IL12B (Interleukin-12 subunit beta)
E132* (p.Glu132Ter) in IL12B (Interleukin-12 subunit beta) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
E132* (p.Glu132Ter) variant details
- p.Glu132Ter
- gnomAD 5-159322482-C-A
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.683
- CADD 36.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available