E108G (p.Glu108Gly) variant of IL12B (Interleukin-12 subunit beta)
E108G (p.Glu108Gly) in IL12B (Interleukin-12 subunit beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
E108G (p.Glu108Gly) variant details
- p.Glu108Gly
- ExAC rs771727370
- gnomAD rs771727370
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.17
- MetaLR 0.08
- MetaSVM -1.00
- CADD 27.30
- PolyPhen-2 0.64
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available