W33C (p.Trp33Cys) variant of IL10RA (Q13651)
W33C (p.Trp33Cys) in IL10RA (Q13651) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
W33C (p.Trp33Cys) variant details
- p.Trp33Cys
- TOPMed rs1281442597
- gnomAD rs1281442597
- Missense
- Variant Prioritization Score for Impact Estimate 0.603
- REVEL 0.51
- MetaLR 0.50
- MetaSVM -0.21
- CADD 31.00
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available